Title : Effects of propofol on various AMPA-, kainate- and NMDA-selective glutamate receptor channels expressed in Xenopus oocytes.

Pub. Date : 1995 Mar 31

PMID : 7609905






2 Functional Relationships(s)
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1 Propofol suppressed the current responses of the alpha 1/alpha 2, beta 2/gamma 2, epsilon 2/zeta 1 and epsilon 3/zeta 1 channels in a dose-dependent manner, whereas it enhanced the current responses of the alpha 1 channel. Propofol MGC75582, possible similarity to act2 S homeolog Xenopus laevis
2 During perfusion of 500 microM propofol, the alpha 1/alpha 2, beta 2/gamma 2, epsilon 2/zeta 1 and epsilon 3/zeta 1 channels were progressively suppressed. Propofol MGC75582, possible similarity to act2 S homeolog Xenopus laevis