Title : The protein kinase C activator TPA modulates cellular levels and distribution of E-cadherin in HT-29 human intestinal epithelial cells.

Pub. Date : 1995 Nov 6

PMID : 7589583






7 Functional Relationships(s)
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1 The protein kinase C activator TPA modulates cellular levels and distribution of E-cadherin in HT-29 human intestinal epithelial cells. Tetradecanoylphorbol Acetate cadherin 1 Homo sapiens
2 We report here that the association of E-cadherin to cytoskeleton, required for the functionality of this protein, increases progressively after seeding; in HT-29 M6 cells 4-5 days were required for detecting most of E-cadherin in the Triton X-100-insoluble (cytoskeleton-associated) fraction. Octoxynol cadherin 1 Homo sapiens
3 We report here that the association of E-cadherin to cytoskeleton, required for the functionality of this protein, increases progressively after seeding; in HT-29 M6 cells 4-5 days were required for detecting most of E-cadherin in the Triton X-100-insoluble (cytoskeleton-associated) fraction. Octoxynol cadherin 1 Homo sapiens
4 The phorbol ester TPA differently affected E-cadherin levels in HT-29 M6 cells; at day 2-3, when most E-cadherin was found not-associated to the cytoskeleton, very important decreases (90%) in the total levels of this protein were detected as soon as 6 h after the addition of this compound. Phorbol Esters cadherin 1 Homo sapiens
5 The phorbol ester TPA differently affected E-cadherin levels in HT-29 M6 cells; at day 2-3, when most E-cadherin was found not-associated to the cytoskeleton, very important decreases (90%) in the total levels of this protein were detected as soon as 6 h after the addition of this compound. Phorbol Esters cadherin 1 Homo sapiens
6 The phorbol ester TPA differently affected E-cadherin levels in HT-29 M6 cells; at day 2-3, when most E-cadherin was found not-associated to the cytoskeleton, very important decreases (90%) in the total levels of this protein were detected as soon as 6 h after the addition of this compound. Tetradecanoylphorbol Acetate cadherin 1 Homo sapiens
7 The phorbol ester TPA differently affected E-cadherin levels in HT-29 M6 cells; at day 2-3, when most E-cadherin was found not-associated to the cytoskeleton, very important decreases (90%) in the total levels of this protein were detected as soon as 6 h after the addition of this compound. Tetradecanoylphorbol Acetate cadherin 1 Homo sapiens