Title : The cyanobacterial toxin microcystin binds covalently to cysteine-273 on protein phosphatase 1.

Pub. Date : 1995 Sep 11

PMID : 7556599






6 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The cyanobacterial toxin microcystin binds covalently to cysteine-273 on protein phosphatase 1. microcystin inorganic pyrophosphatase 1 Homo sapiens
2 The interaction between protein phosphatase 1 (PP1) and microcystin (MC) was stable in 1% SDS or 70% formic acid indicative of a covalent interaction. microcystin inorganic pyrophosphatase 1 Homo sapiens
3 The interaction between protein phosphatase 1 (PP1) and microcystin (MC) was stable in 1% SDS or 70% formic acid indicative of a covalent interaction. microcystin inorganic pyrophosphatase 1 Homo sapiens
4 The interaction between protein phosphatase 1 (PP1) and microcystin (MC) was stable in 1% SDS or 70% formic acid indicative of a covalent interaction. microcystin inorganic pyrophosphatase 1 Homo sapiens
5 The interaction between protein phosphatase 1 (PP1) and microcystin (MC) was stable in 1% SDS or 70% formic acid indicative of a covalent interaction. microcystin inorganic pyrophosphatase 1 Homo sapiens
6 Here we isolate the MC-binding peptide and demonstrate that Cys273 of PP1 binds covalently to the methyl-dehydroalanine (Mdha) residue of the toxin. microcystin inorganic pyrophosphatase 1 Homo sapiens