Title : Secretion of recombinant human IgE-Fc by mammalian cells and biological activity of glycosylation site mutants.

Pub. Date : 1995 Feb

PMID : 7543206






1 Functional Relationships(s)
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1 Both the double mutant and wild-type hIgE-Fc bind to the high-affinity IgE receptor, Fc epsilon RI, with about the same affinity as myeloma IgE (Ka in the range 10(10)-10(11) M-1), and were able to sensitize isolated human basophils for anti-IgE triggering of histamine release. Histamine Fc epsilon receptor Ia Homo sapiens