Pub. Date : 1995 Jan
PMID : 7530414
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | RESULTS: Both substance P binding and Ca2+ increase were inhibited half-maximally by approximately 1 mM bupivacaine at pH 7.5, whereas tetracaine, lidocaine, and benzocaine were slightly less potent at inhibiting binding. | Bupivacaine | tachykinin 1 | Mus musculus |
| 2 | Concentration-dependent substance P-binding studies showed that bupivacaine"s inhibition was not competitive. | Bupivacaine | tachykinin 1 | Mus musculus |
| 3 | Inhibition of substance P binding by bupivacaine increased with increasing pH, but the protonated species appears to have some inhibitory activity, and quaternary lidocaine also inhibited binding. | Bupivacaine | tachykinin 1 | Mus musculus |