Pub. Date : 1994 Dec
PMID : 7525608
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Beta 2 integrin-dependent tyrosine phosphorylation of paxillin in human neutrophils treated with tumor necrosis factor. | Tyrosine | paxillin | Homo sapiens |
| 2 | The focal adhesion protein paxillin undergoes tyrosine phosphorylation in response to signals mediated by integrins, neuropeptides and oncogene products, possibly via activation of the focal adhesion-associated kinase, p125FAK. | Tyrosine | paxillin | Homo sapiens |
| 3 | In the present work, tumor necrosis factor-alpha (TNF) stimulated tyrosine phosphorylation of paxillin in human neutrophils. | Tyrosine | paxillin | Homo sapiens |
| 4 | Adherent neutrophils also tyrosine phosphorylated paxillin in response to phorbol ester, formylmethionyl-leucyl-phenylalanine and opsonized bacteria. | Tyrosine | paxillin | Homo sapiens |
| 5 | Adherent neutrophils also tyrosine phosphorylated paxillin in response to phorbol ester, formylmethionyl-leucyl-phenylalanine and opsonized bacteria. | Phorbol Esters | paxillin | Homo sapiens |
| 6 | Adherent neutrophils also tyrosine phosphorylated paxillin in response to phorbol ester, formylmethionyl-leucyl-phenylalanine and opsonized bacteria. | N-Formylmethionine Leucyl-Phenylalanine | paxillin | Homo sapiens |
| 7 | Thus, cytokines and microbial products are among the stimuli that can induce the tyrosine phosphorylation of paxillin, and kinases other than p125FAK may be responsible. | Tyrosine | paxillin | Homo sapiens |
| 8 | This is the first identification of paxillin and p125FAK in human cells and neutrophils, and one of the few identifications of a specific protein that undergoes tyrosine phosphorylation in response to any agonist in neutrophils or in response to TNF in any cell. | Tyrosine | paxillin | Homo sapiens |