Title : Dual mechanism for the control of inducible-type NO synthase gene expression in macrophages during activation by interferon-gamma and bacterial lipopolysaccharide. Transcriptional and post-transcriptional regulation.

Pub. Date : 1994 Mar 18

PMID : 7510685






1 Functional Relationships(s)
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1 Production of nitric oxide (NO) by macrophages is enhanced upon activation by bacterial endotoxins and cytokines mainly via an increase of the intracellular content of the inducible isoform of nitric oxide synthase (i-NOS). Nitric Oxide nitric oxide synthase 2, inducible Mus musculus