Title : Inducible nitric oxide synthase is increased in murine lung epithelial cells by cytokine stimulation.

Pub. Date : 1994 Feb 15

PMID : 7509602






3 Functional Relationships(s)
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1 Stimulation with cytomix, a combination of interleukin-1 beta, tumor necrosis factor-alpha, and interferon-gamma, elevated nitrite levels by 873% in the culture supernatants and enhanced the conversion of arginine to citrulline by 273% at 24 h. An increased number of cells stained for iNOS and an increase in iNOS mRNA was also observed. cytomix nitric oxide synthase 2, inducible Mus musculus
2 Stimulation with cytomix, a combination of interleukin-1 beta, tumor necrosis factor-alpha, and interferon-gamma, elevated nitrite levels by 873% in the culture supernatants and enhanced the conversion of arginine to citrulline by 273% at 24 h. An increased number of cells stained for iNOS and an increase in iNOS mRNA was also observed. cytomix nitric oxide synthase 2, inducible Mus musculus
3 Dexamethasone decreased the cytokine-induced increase in nitrite levels, NOS activity, iNOS immunoreactivity, and mRNA but did not change the half life of iNOS mRNA. Dexamethasone nitric oxide synthase 2, inducible Mus musculus