Title : The proline-rich region of Vav binds to Grb2 and Grb3-3.

Pub. Date : 1995 Oct 19

PMID : 7478592






3 Functional Relationships(s)
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Compound Name
Protein Name
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1 The proline-rich region of Vav binds to Grb2 and Grb3-3. Proline growth factor receptor bound protein 2 Mus musculus
2 By the use of an in vivo genetic approach (the double hybrid system) and through in vitro experiments (glutathione-S-transferase fusion proteins) we furnish evidence that the interaction between Vav and Grb2 involves the C-SH3 domain of Grb2 and the proline-rich region located in the N-SH3 of Vav. Proline growth factor receptor bound protein 2 Mus musculus
3 By the use of an in vivo genetic approach (the double hybrid system) and through in vitro experiments (glutathione-S-transferase fusion proteins) we furnish evidence that the interaction between Vav and Grb2 involves the C-SH3 domain of Grb2 and the proline-rich region located in the N-SH3 of Vav. Proline growth factor receptor bound protein 2 Mus musculus