Title : Glutathione redox cycle protects cultured endothelial cells against lysis by extracellularly generated hydrogen peroxide.

Pub. Date : 1984 Mar

PMID : 6707200






5 Functional Relationships(s)
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Protein Name
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1 Endothelial glutathione reductase was selectively inhibited with 1,3-bis(chloroethyl)-1-nitrosourea (BCNU). Carmustine glutathione-disulfide reductase Bos taurus
2 Endothelial glutathione reductase was selectively inhibited with 1,3-bis(chloroethyl)-1-nitrosourea (BCNU). Carmustine glutathione-disulfide reductase Bos taurus
3 Glucose-glucose oxidase-mediated lysis of BCNU-treated bovine endothelial cells was catalase-inhibitable and directly related to BCNU concentration and endogenous glutathione reductase activity. Carmustine glutathione-disulfide reductase Bos taurus
4 Inhibition of endothelial glutathione reductase by BCNU or depletion of reduced glutathione by BSO increased endothelial susceptibility to lysis by hydrogen peroxide generated by phorbol myristate acetate-activated neutrophils. Carmustine glutathione-disulfide reductase Bos taurus
5 Inhibition of endothelial glutathione reductase by BCNU or depletion of reduced glutathione by BSO increased endothelial susceptibility to lysis by hydrogen peroxide generated by phorbol myristate acetate-activated neutrophils. Hydrogen Peroxide glutathione-disulfide reductase Bos taurus