Title : Role of diamine oxidase during the treatment of tumour-bearing mice with combinations of polyamine anti-metabolites.

Pub. Date : 1983 Jun 15

PMID : 6411077






2 Functional Relationships(s)
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1 Experiments carried out with the combination of difluoromethylornithine and aminoguanidine, a potent inhibitor of diamine oxidase (EC 1.4.3.6), indicated that the methylglyoxal bis(guanylhydrazone)-induced reversal of polyamine depletion was mediated by the known inhibition of diamine oxidase by the diguanidine. pimagedine amine oxidase, copper-containing 1 Mus musculus
2 Experiments carried out with the combination of difluoromethylornithine and aminoguanidine, a potent inhibitor of diamine oxidase (EC 1.4.3.6), indicated that the methylglyoxal bis(guanylhydrazone)-induced reversal of polyamine depletion was mediated by the known inhibition of diamine oxidase by the diguanidine. pimagedine amine oxidase, copper-containing 1 Mus musculus