Title : 5-azacytidine selectively increases gamma-globin synthesis in a patient with beta+ thalassemia.

Pub. Date : 1982 Dec 9

PMID : 6183586






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 5-azacytidine selectively increases gamma-globin synthesis in a patient with beta+ thalassemia. Azacitidine hemoglobin subunit gamma 1 Homo sapiens
2 After seven days of 5-azacytidine treatment, gamma-globin synthesis increased approximately sevenfold, temporarily normalizing the patient"s unbalanced globin synthesis. Azacitidine hemoglobin subunit gamma 1 Homo sapiens
3 5-Azacytidine selectivity increases gamma-globin synthesis and therefore provides a new approach to the treatment of severe beta-thalassemia. Azacitidine hemoglobin subunit gamma 1 Homo sapiens