Title : The influence of estrogen and prolactin on Hageman factor (factor XII) titer in ovariectomized and hypophysectomized rats.

Pub. Date : 1985 Sep

PMID : 4027381






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Rats were ovariectomized to minimize the influence of endogenous estrogen and progesterone on the Hageman factor titer. Progesterone coagulation factor XII Rattus norvegicus
2 In contrast, the infusion of 17 beta-estradiol induced a marked elevation of the plasma Hageman factor titer, as measured functionally and immunologically. Estradiol coagulation factor XII Rattus norvegicus
3 In hypophysectomized ovariectomized animals, the administration of estradiol restored the Hageman factor titer to normal levels, whereas the infusion of prolactin induced a dramatic rise in the Hageman factor titer to the degree observed in nonhypophysectomized estrogen-treated rats. Estradiol coagulation factor XII Rattus norvegicus