Title : Mechanisms regulating cell resistance to adriamycin. Evidence that drug accumulation in resistant cells is modulated by phosphorylation of a plasma membrane glycoprotein.

Pub. Date : 1985 May 1

PMID : 3994760






2 Functional Relationships(s)
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1 Incubation of adriamycin resistant Chinese hamster lung cells with the calmodulin inhibitor trifluoperazine (TFP) resulted in a significant increase in the cellular accumulation of drug. Doxorubicin LOC100759184 Cricetulus griseus
2 Incubation of adriamycin resistant Chinese hamster lung cells with the calmodulin inhibitor trifluoperazine (TFP) resulted in a significant increase in the cellular accumulation of drug. Trifluoperazine LOC100759184 Cricetulus griseus