Pub. Date : 1986 Jul
PMID : 3708569
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Prevention of 1-(3-deoxycytidyl),2-(1-deoxyguanosinyl)ethane cross-link formation in DNA by rat liver O6-alkylguanine-DNA alkyltransferase. | 1-(3-deoxycytidyl) | O-6-methylguanine-DNA methyltransferase | Rattus norvegicus |
| 2 | Prevention of 1-(3-deoxycytidyl),2-(1-deoxyguanosinyl)ethane cross-link formation in DNA by rat liver O6-alkylguanine-DNA alkyltransferase. | 2-(1-deoxyguanosinyl)ethane | O-6-methylguanine-DNA methyltransferase | Rattus norvegicus |
| 3 | To investigate the role of O6-alkylguanine-DNA alkyltransferase in preventing the formation of this cross-link, a DNA substrate containing O6-fluoroethylguanine has been prepared by reacting DNA with N-2-fluoroethyl-N"-cyclohexyl-N-nitrosourea. | o6-fluoroethylguanine | O-6-methylguanine-DNA methyltransferase | Rattus norvegicus |
| 4 | To investigate the role of O6-alkylguanine-DNA alkyltransferase in preventing the formation of this cross-link, a DNA substrate containing O6-fluoroethylguanine has been prepared by reacting DNA with N-2-fluoroethyl-N"-cyclohexyl-N-nitrosourea. | n-2-fluoroethyl-n"-cyclohexyl-n-nitrosourea | O-6-methylguanine-DNA methyltransferase | Rattus norvegicus |