Title : Cynarin suppresses gouty arthritis induced by monosodium urate crystals.

Pub. Date : 2022 May

PMID : 35546047






1 Functional Relationships(s)
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1 Cyn treatment reduced hind paw swelling and M1 macrophage infiltration, suppressed the mRNA expression of inflammatory factors, and inhibited NLRP3 inflammasome activation in vivo, in addition to inhibiting the phosphorylation of IKKa/beta, p65, and c-Jun NH 2-terminal kinase (JNK). cynarine v-rel reticuloendotheliosis viral oncogene homolog A (avian) Mus musculus