Title : An overview of the pharmacology of imipenem/cilastatin.

Pub. Date : 1986 Dec

PMID : 3546249






1 Functional Relationships(s)
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1 Since it is hydrolysed by dehydropeptidase-I, a zinc metallo-enzyme resident in the brush border of the renal tubule, it is co-administered with cilastatin, a reversible inhibitor of this enzyme. Cilastatin dipeptidase 1 Homo sapiens