Pub. Date : 2022 Apr 22
PMID : 35460083
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Pharmacology, safety, efficacy and clinical uses of the COX-2 inhibitor robenacoxib. | robenacoxib | cytochrome c oxidase subunit II | Canis lupus familiaris |
| 2 | Robenacoxib inhibits the cyclooxygenase (COX)-2 isoform of COX selectively (in vitro IC50 ratios COX-1:COX-2, 129:1 in dogs, 32:1 in cats). | robenacoxib | cytochrome c oxidase subunit II | Canis lupus familiaris |
| 3 | Robenacoxib inhibits the cyclooxygenase (COX)-2 isoform of COX selectively (in vitro IC50 ratios COX-1:COX-2, 129:1 in dogs, 32:1 in cats). | robenacoxib | cytochrome c oxidase subunit I | Canis lupus familiaris |
| 4 | Robenacoxib inhibits the cyclooxygenase (COX)-2 isoform of COX selectively (in vitro IC50 ratios COX-1:COX-2, 129:1 in dogs, 32:1 in cats). | robenacoxib | cytochrome c oxidase subunit II | Canis lupus familiaris |
| 5 | At registered dosages (2 mg/kg subcutaneously in dogs and cats, 1-4 mg/kg orally in dogs and 1-2.4 mg/kg orally in cats), robenacoxib produces significant inhibition of COX-2 whilst sparing COX-1. | robenacoxib | cytochrome c oxidase subunit II | Felis catus |
| 6 | At registered dosages (2 mg/kg subcutaneously in dogs and cats, 1-4 mg/kg orally in dogs and 1-2.4 mg/kg orally in cats), robenacoxib produces significant inhibition of COX-2 whilst sparing COX-1. | robenacoxib | cytochrome c oxidase subunit I | Felis catus |