Pub. Date : 2022 Apr 15
PMID : 35325610
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Bisphenol A exposure triggers the malignant transformation of prostatic hyperplasia in beagle dogs via cfa-miR-204/KRAS axis. | bis(4-hydroxyphenyl)sulfone | KRAS proto-oncogene, GTPase | Canis lupus familiaris |
2 | Based on microRNA (miRNA) microarray screening and functional enrichment analysis, BPA might facilitate the progression of prostate tumorigenesis in beagle dogs via cfa-miR-204 and its downstream target KRAS oncogene. | bisphenol A | KRAS proto-oncogene, GTPase | Canis lupus familiaris |
3 | These findings provide a series of underlying targets for preventing the initiation and metastasis of BPA-induced prostatic hyperplasia and tumorigenesis, while the regulatory relationship headed with KRAS requires further investigation. | bisphenol A | KRAS proto-oncogene, GTPase | Canis lupus familiaris |