Title : Membrane permeabilization is mediated by distinct epitopes in mouse and human orthologs of the necroptosis effector, MLKL.

Pub. Date : 2022 Mar 9

PMID : 35264780






1 Functional Relationships(s)
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1 Using liposome permeabilization and cell death assays, we validate K69 in the alpha3 helix, W108 in the alpha4 helix, and R137/Q138 in the first brace helix as crucial residues for necroptotic signaling. k69 immunoglobulin kappa variable 2D-28 Homo sapiens