Title : MCPIP1 regulates focal adhesion kinase and Rho GTPase-dependent migration in clear cell renal cell carcinoma.

Pub. Date : 2022 May 5

PMID : 35257717






5 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 MCPIP1 decreases the levels of Rho GTPases and reduces the phosphorylation of FAK at Tyr-397 and Tyr-861 and Src at Tyr-418. Tyrosine zinc finger CCCH-type containing 12A Homo sapiens
2 MCPIP1 decreases the levels of Rho GTPases and reduces the phosphorylation of FAK at Tyr-397 and Tyr-861 and Src at Tyr-418. Tyrosine zinc finger CCCH-type containing 12A Homo sapiens
3 MCPIP1 decreases the levels of Rho GTPases and reduces the phosphorylation of FAK at Tyr-397 and Tyr-861 and Src at Tyr-418. Tyrosine zinc finger CCCH-type containing 12A Homo sapiens
4 The loss of MCPIP1 RNase activity results in actin remodeling, an increase in the levels of Rho proteins and the phosphorylation of FAK on Tyr-397, which leads to Tyr-418 Src phosphorylation and an increase in migration activity. Tyrosine zinc finger CCCH-type containing 12A Homo sapiens
5 The loss of MCPIP1 RNase activity results in actin remodeling, an increase in the levels of Rho proteins and the phosphorylation of FAK on Tyr-397, which leads to Tyr-418 Src phosphorylation and an increase in migration activity. Tyrosine zinc finger CCCH-type containing 12A Homo sapiens