Title : [Integrin α3β1 signaling in regulation of the SK-Mel-147 melanoma cell senescence].

Pub. Date : 2022 Jan

PMID : 35221295






2 Functional Relationships(s)
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1 Pharmacological inhibition of mTORC1 reduced the number SA-beta-Gal-positive cells in the SK-Mel-147 cell population depleted of alpha3beta1. 2-(2-quinolinyl)-1H-indene--1,3(2H)-dione-6'-sulfonic acid CREB regulated transcription coactivator 1 Mus musculus
2 It appeared that in the cell population with downregulated alpha3beta1, inhibition of Akt1 reduced the number SA-beta-Gal positive cells to the level of control cell population, while inhibition of Akt2 had no visible effect. 2-(2-quinolinyl)-1H-indene--1,3(2H)-dione-6'-sulfonic acid AKT serine/threonine kinase 1 Homo sapiens