Title : A Critical Balance Between PAX8 and the Hippo Mediator TAZ Determines Sodium/Iodide Symporter Expression and Function.

Pub. Date : 2022 Mar

PMID : 34726504






4 Functional Relationships(s)
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1 A critical balance between Pax8 and the Hippo mediator TAZ determines sodium-iodide symporter NIS expression and function. Sodium Iodide tafazzin, phospholipid-lysophospholipid transacylase Mus musculus
2 TSH via cAMP activated Hippo signaling pathway and, consequently, TAZ was excluded from the nucleus. Thyrotropin tafazzin, phospholipid-lysophospholipid transacylase Mus musculus
3 TSH via cAMP activated Hippo signaling pathway and, consequently, TAZ was excluded from the nucleus. Cyclic AMP tafazzin, phospholipid-lysophospholipid transacylase Mus musculus
4 Conversely, TAZ nuclear retention was promoted by TGFbeta, a potent NIS repressor, and TAZ silencing markedly relieved the TGFbeta-induced inhibition of the symporter. Nickel tafazzin, phospholipid-lysophospholipid transacylase Mus musculus