Title : Multitarget 2'-hydroxychalcones as potential drugs for the treatment of neurodegenerative disorders and their comorbidities.

Pub. Date : 2021 Dec 15

PMID : 34653442






3 Functional Relationships(s)
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1 We report here the synthesis of 2"-hydroxychalcones as MAO-A and MAO-B inhibitors. 2'-hydroxychalcone monoamine oxidase A Mus musculus
2 We report here the synthesis of 2"-hydroxychalcones as MAO-A and MAO-B inhibitors. 2'-hydroxychalcone monoamine oxidase B Mus musculus
3 Molecular modelling rationalised the binding mode of 2"-hydroxychalcones in the active site of hMAO-B. 2'-hydroxychalcone monoamine oxidase B Homo sapiens