Pub. Date : 2021 Dec 1
PMID : 34508829
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In addition, we analyzed that the mRNA level of PDE5 was positively correlated with YAP/TAZ based on TCGA database and demonstrated tadalafil, a PDE5 inhibitor, could block YAP/TAZ protein expression by activating Hippo pathway. | Tadalafil | tafazzin, phospholipid-lysophospholipid transacylase | Mus musculus |
| 2 | In addition, we analyzed that the mRNA level of PDE5 was positively correlated with YAP/TAZ based on TCGA database and demonstrated tadalafil, a PDE5 inhibitor, could block YAP/TAZ protein expression by activating Hippo pathway. | Tadalafil | tafazzin, phospholipid-lysophospholipid transacylase | Mus musculus |
| 3 | Cotreatment with tadalafil and JQ-1 synergistically reduced YAP/TAZ protein expression, suppressed proliferation and induced G0-G1 arrest of cultured HCC cells. | Tadalafil | tafazzin, phospholipid-lysophospholipid transacylase | Mus musculus |