Title : P2Y12 receptor blockers are anti-inflammatory drugs inhibiting both circulating monocytes and macrophages including THP-1 cells.

Pub. Date : 2021 Aug 31

PMID : 34465804






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Mediated by platelets, ADP results in activation of the integrin receptor Mac-1 on blood monocytes, as detected by the conformation-specific single-chain antibody MAN-1. Adenosine Diphosphate LEM domain containing 3 Homo sapiens