Title : PD-L1+ and XCR1+ dendritic cells are region-specific regulators of gut homeostasis.

Pub. Date : 2021 Aug 13

PMID : 34389726






1 Functional Relationships(s)
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1 Mice lacking PD-L1+ and XCR1+ DC have a proinflammatory gut milieu associated with an increase in Th1/Th17 cells and a decrease in Treg cells and have exacerbated disease in the models of 5-FU-induced mucositis and DSS-induced colitis. Fluorouracil chemokine (C motif) receptor 1 Mus musculus