Title : Knockdown of microRNA-130b improves doxorubicin sensitivity in bladder urothelial carcinoma by negatively regulating cylindromatosis expression.

Pub. Date : 2021

PMID : 34336031






12 Functional Relationships(s)
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1 Knockdown of microRNA-130b improves doxorubicin sensitivity in bladder urothelial carcinoma by negatively regulating cylindromatosis expression. Doxorubicin microRNA 130b Homo sapiens
2 Results: Our study found that miR-130b was up-regulated in doxorubicin-insensitive BUC tissues and cell lines, and its high expression was negatively related to doxorubicin sensitivity in BUC. Doxorubicin microRNA 130b Homo sapiens
3 Results: Our study found that miR-130b was up-regulated in doxorubicin-insensitive BUC tissues and cell lines, and its high expression was negatively related to doxorubicin sensitivity in BUC. Doxorubicin microRNA 130b Homo sapiens
4 The miR-130b knockdown reduced the IC50 of doxorubicin and improved doxorubicin sensitivity of J82/Dox and T24/Dox cells. Doxorubicin microRNA 130b Homo sapiens
5 The miR-130b knockdown reduced the IC50 of doxorubicin and improved doxorubicin sensitivity of J82/Dox and T24/Dox cells. Doxorubicin microRNA 130b Homo sapiens
6 The miR-130b knockdown reduced the IC50 of doxorubicin and improved doxorubicin sensitivity of J82/Dox and T24/Dox cells. Doxorubicin microRNA 130b Homo sapiens
7 The miR-130b knockdown reduced the IC50 of doxorubicin and improved doxorubicin sensitivity of J82/Dox and T24/Dox cells. Doxorubicin microRNA 130b Homo sapiens
8 Knockdown of CYLD reversed miR-130b"s regulatory roles in doxorubicin sensitivity in J82/Dox and T24/Dox cells. Doxorubicin microRNA 130b Homo sapiens
9 Knockdown of CYLD reversed miR-130b"s regulatory roles in doxorubicin sensitivity in J82/Dox and T24/Dox cells. Doxorubicin microRNA 130b Homo sapiens
10 Knockdown of CYLD reversed miR-130b"s regulatory roles in doxorubicin sensitivity in J82/Dox and T24/Dox cells. Doxorubicin microRNA 130b Homo sapiens
11 Conclusions: High expression of miR-130b is negatively related to doxorubicin sensitivity in BUC, and knockdown of miR-130b improves doxorubicin sensitivity in BUC by negatively regulating CYLD expression. Doxorubicin microRNA 130b Homo sapiens
12 Conclusions: High expression of miR-130b is negatively related to doxorubicin sensitivity in BUC, and knockdown of miR-130b improves doxorubicin sensitivity in BUC by negatively regulating CYLD expression. Doxorubicin microRNA 130b Homo sapiens