Title : Alantolactone is a natural product that potently inhibits YAP1/TAZ through promotion of reactive oxygen species accumulation.

Pub. Date : 2021 Oct

PMID : 34289205






1 Functional Relationships(s)
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1 We also tested 16 other structural derivatives of ALT and found that natural ALT was the most efficient at increasing ROS-induced LATS kinase activities and thus YAP1/TAZ phosphorylation. ros tafazzin, phospholipid-lysophospholipid transacylase Mus musculus