Pub. Date : 2021 Aug
PMID : 34286514
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | MATERIAL AND METHODS: Expression of the lncRNA PCGEM1, together with miR-129-5p, and the mRNA level of ETV1 and drug resistance-related genes including LRPA, MDR1 and MDR3 were determined using quantitative real-time polymerase chain reaction (RT-qPCR) in an oxaliplatin-resistant HCC cell line (Hep3B/OXA). | Oxaliplatin | microRNA 1295a | Homo sapiens |
| 2 | CONCLUSIONS: Our findings demonstrated that PCGEM1 modulated oxaliplatin resistance by targeting the miR-129-5p/ETV1 pathway in HCC in vitro, suggesting a potential strategy for the treatment of chemoresistant HCC. | Oxaliplatin | microRNA 1295a | Homo sapiens |