Pub. Date : 2021 Jun 16
PMID : 34132932
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Temozolomide (TMZ)-resistant GBM cells were established and transfected with relative plasmid to alter OIP5-AS1, IGF2BP2 or miR-129-5p expression. | Temozolomide | microRNA 1295a | Homo sapiens |
| 2 | Temozolomide (TMZ)-resistant GBM cells were established and transfected with relative plasmid to alter OIP5-AS1, IGF2BP2 or miR-129-5p expression. | Temozolomide | microRNA 1295a | Homo sapiens |
| 3 | OIP5-AS1 silencing or miR-129-5p overexpression inhibited GBM cell chemoresistance to TMZ and proliferation, and promoted cell apoptosis. | Temozolomide | microRNA 1295a | Homo sapiens |
| 4 | CONCLUSION: OIP5-AS1 inhibition upregulated miR-129-5p to repress resistance to TMZ in GBM cells via downregulating IGF2BP2. | Temozolomide | microRNA 1295a | Homo sapiens |