Title : YAP/TAZ Suppress Drug Penetration Into Hepatocellular Carcinoma Through Stromal Activation.

Pub. Date : 2021 Nov

PMID : 34101869






3 Functional Relationships(s)
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1 Murine HCC models developed by HT methods showed that a high YAP/TAZ activity in HCC cells impaired verteporfin penetration into the cancer. Verteporfin tafazzin, phospholipid-lysophospholipid transacylase Mus musculus
2 Consistent with the findings in the in vivo models of HCC, MCHOs with activated YAP/TAZ signaling showed stromal activation and impaired penetration of verteporfin into the tumor organoids. mchos tafazzin, phospholipid-lysophospholipid transacylase Mus musculus
3 Consistent with the findings in the in vivo models of HCC, MCHOs with activated YAP/TAZ signaling showed stromal activation and impaired penetration of verteporfin into the tumor organoids. Verteporfin tafazzin, phospholipid-lysophospholipid transacylase Mus musculus