Title : Circ-PNPT1 contributes to gestational diabetes mellitus (GDM) by regulating the function of trophoblast cells through miR-889-3p/PAK1 axis.

Pub. Date : 2021 Jun 1

PMID : 34074335






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The binding interaction between miR-889-3p and circ-PNPT1 or PAK1 was verified using dual-luciferase reporter, RNA immunoprecipitation (RIP) and RNA pull-down assays. mir-889 polyribonucleotide nucleotidyltransferase 1 Homo sapiens
2 RESULTS: Circ-PNPT1 was highly expressed in the placental tissues of GDM and high glucose (HG)-induced trophoblast cells. Glucose polyribonucleotide nucleotidyltransferase 1 Homo sapiens