Pub. Date : 2021 May 31
PMID : 34059001
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Knockdown of KLK11 in mouse hearts inhibited TAC-induced decline in fraction shortening and ejection fraction, reduced the increase in heart weight, cardiomyocyte size, and expression of hypertrophic fetal genes. | tac | kallikrein related-peptidase 11 | Mus musculus |
| 2 | Repression of mTOR with rapamycin blocked the effects of KLK11 on S6K1 and 4EBP1 as well as protein synthesis. | Sirolimus | kallikrein related-peptidase 11 | Mus musculus |
| 3 | Besides, rapamycin treatment blocked the roles of KLK11 in the regulation of cardiomyocyte hypertrophy. | Sirolimus | kallikrein related-peptidase 11 | Mus musculus |