Pub. Date : 2021
PMID : 33996960
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In HepG2 cells, we identified 62 significantly differentially expressed genes (DEGs) (6,564 transcripts) and 319 lncRNAs (124 known lncRNAs and 195 novel lncRNAs) that were affected by ORF3, which were involved in systemic lupus erythematosus, Staphylococcus aureus infection, signaling pathways pluripotency regulation of stem cells, the peroxisome proliferator-activated receptor (PPAR) signaling pathway, and platinum drug resistance pathways. | Platinum | ankyrin repeat, SAM and basic leucine zipper domain containing 1 | Homo sapiens |
| 2 | Our results revealed that the lncRNA profile in host cells affected by ORF3, swine HEV ORF3, might affect the pentose and glucuronate interconversions and mediate the formation of obstructive jaundice by influencing bile secretion, which will help to determine the function of ORF3 and the infection mechanism and treatment of swine HE. | Pentoses | ankyrin repeat, SAM and basic leucine zipper domain containing 1 | Homo sapiens |
| 3 | Our results revealed that the lncRNA profile in host cells affected by ORF3, swine HEV ORF3, might affect the pentose and glucuronate interconversions and mediate the formation of obstructive jaundice by influencing bile secretion, which will help to determine the function of ORF3 and the infection mechanism and treatment of swine HE. | Pentoses | ankyrin repeat, SAM and basic leucine zipper domain containing 1 | Homo sapiens |
| 4 | Our results revealed that the lncRNA profile in host cells affected by ORF3, swine HEV ORF3, might affect the pentose and glucuronate interconversions and mediate the formation of obstructive jaundice by influencing bile secretion, which will help to determine the function of ORF3 and the infection mechanism and treatment of swine HE. | Pentoses | ankyrin repeat, SAM and basic leucine zipper domain containing 1 | Homo sapiens |
| 5 | Our results revealed that the lncRNA profile in host cells affected by ORF3, swine HEV ORF3, might affect the pentose and glucuronate interconversions and mediate the formation of obstructive jaundice by influencing bile secretion, which will help to determine the function of ORF3 and the infection mechanism and treatment of swine HE. | Glucuronic Acid | ankyrin repeat, SAM and basic leucine zipper domain containing 1 | Homo sapiens |
| 6 | Our results revealed that the lncRNA profile in host cells affected by ORF3, swine HEV ORF3, might affect the pentose and glucuronate interconversions and mediate the formation of obstructive jaundice by influencing bile secretion, which will help to determine the function of ORF3 and the infection mechanism and treatment of swine HE. | Glucuronic Acid | ankyrin repeat, SAM and basic leucine zipper domain containing 1 | Homo sapiens |
| 7 | Our results revealed that the lncRNA profile in host cells affected by ORF3, swine HEV ORF3, might affect the pentose and glucuronate interconversions and mediate the formation of obstructive jaundice by influencing bile secretion, which will help to determine the function of ORF3 and the infection mechanism and treatment of swine HE. | Glucuronic Acid | ankyrin repeat, SAM and basic leucine zipper domain containing 1 | Homo sapiens |