Title : Increased AT1 receptor expression mediates vasoconstriction leading to hypertension in Snx1-/- mice.

Pub. Date : 2021 Aug

PMID : 33972750






4 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Sorting nexin 1 (SNX1) participates in the sorting and trafficking of the renal dopamine D5 receptor, while angiotensin and dopamine are counterregulatory factors in the regulation of blood pressure. Dopamine sorting nexin 1 Mus musculus
2 Sorting nexin 1 (SNX1) participates in the sorting and trafficking of the renal dopamine D5 receptor, while angiotensin and dopamine are counterregulatory factors in the regulation of blood pressure. Dopamine sorting nexin 1 Mus musculus
3 In vitro studies revealed that AT1R protein levels and downstream calcium signaling were upregulated in A10 cells treated with SNX1 siRNA. Calcium sorting nexin 1 Mus musculus
4 AT1R protein was less degraded when SNX1 was downregulated, as reflected by a cycloheximide chase assay. Cycloheximide sorting nexin 1 Mus musculus