Title : ALG3 contributes to stemness and radioresistance through regulating glycosylation of TGF-β receptor II in breast cancer.

Pub. Date : 2021 Apr 30

PMID : 33931075






2 Functional Relationships(s)
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1 Importantly, both attenuation of glycosylation using tunicamycin and inhibition of TGFBR2 using LY2109761 differentially abrogated the stimulatory effect of ALG3 overexpression on cancer stemness and radioresistance. Tunicamycin ALG3 alpha-1,3- mannosyltransferase Homo sapiens
2 Importantly, both attenuation of glycosylation using tunicamycin and inhibition of TGFBR2 using LY2109761 differentially abrogated the stimulatory effect of ALG3 overexpression on cancer stemness and radioresistance. LY2109761 ALG3 alpha-1,3- mannosyltransferase Homo sapiens