Pub. Date : 2021
PMID : 33828639
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Melatonin bound to Mel1a and Mel1c and upregulated p-AKT, p-PKC, and p-ERK expression, thereby activating PI3K/AKT and PKC/ERK signaling and inducing B-lymphocyte proliferation. | Melatonin | melatonin receptor 1A | Gallus gallus |
2 | Overall, these findings suggested that melatonin modulates a combination of green and blue light-induced B-lymphocyte proliferation in chickens by reducing oxidative stress and activating the Mel1a/PI3K/AKT and Mel1c/PKC/ERK pathways. | Melatonin | melatonin receptor 1A | Gallus gallus |