Title : Deciphering the Role of Intestinal Crypt Cell Populations in Resistance to Chemotherapy.

Pub. Date : 2021 May 15

PMID : 33741693






1 Functional Relationships(s)
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1 Engineered mouse models treated with the therapeutic agent 5-fluorouracil showed that upon increased MSI1 levels, Lgr5high-SCs remain sensitive while Lgr5low-progenitors reprogram to a drug-resistant phenotype. Fluorouracil musashi RNA-binding protein 1 Mus musculus