Pub. Date : 2021 Apr
PMID : 33655336
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Radiation treatment- or Ca2+ ionophore A23187-induced apoptosis was significantly inhibited in <em>CRMP4</em>-deficient cells, including radiation-resistant or <em>CRMP4</em>-shRNA cell lines. | Calcimycin | dihydropyrimidinase like 3 | Homo sapiens |
| 2 | Radiation treatment- or Ca2+ ionophore A23187-induced apoptosis was significantly inhibited in <em>CRMP4</em>-deficient cells, including radiation-resistant or <em>CRMP4</em>-shRNA cell lines. | Calcimycin | dihydropyrimidinase like 3 | Homo sapiens |
| 3 | Furthermore, treatment of <em>CRMP4</em>-deficient cells with low levels (<5 microM) of BAPTA-AM, a Ca2+ chelator, resulted in radiation resistance. | 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester | dihydropyrimidinase like 3 | Homo sapiens |
| 4 | Conversely, Ca2+ deficiency induced by a high BAPTA-AM concentration (>10 microM) resulted in higher cell death in the <em>CRMP4</em>-depleted cells compared to <em>CRMP4</em>-expressing control cells. | 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester | dihydropyrimidinase like 3 | Homo sapiens |