Title : Extra copy of the mitochondrial cytochrome-c peroxidase gene confers a pyruvate-underproducing characteristic of sake yeast through respiratory metabolism.

Pub. Date : 2021 Jun

PMID : 33597082






5 Functional Relationships(s)
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1 Extra copy of the mitochondrial cytochrome-c peroxidase gene confers a pyruvate-underproducing characteristic of sake yeast through respiratory metabolism. Pyruvic Acid cytochrome-c peroxidase Saccharomyces cerevisiae S288C
2 In this report, we found that increased copy number of CCP1, which is located on chromosome XI and encodes cytochrome-c peroxidase, decreased the pyruvate productivity of sake yeasts. Pyruvic Acid cytochrome-c peroxidase Saccharomyces cerevisiae S288C
3 In this report, we found that increased copy number of CCP1, which is located on chromosome XI and encodes cytochrome-c peroxidase, decreased the pyruvate productivity of sake yeasts. Pyruvic Acid cytochrome-c peroxidase Saccharomyces cerevisiae S288C
4 Introducing an extra copy of CCP1 activated respiratory metabolism governed by Hap4 and increased reactive oxygen species. Reactive Oxygen Species cytochrome-c peroxidase Saccharomyces cerevisiae S288C
5 Therefore, it was concluded that increased copy number of CCP1 on chromosome XI activated respiratory metabolism and decreased pyruvate levels in an aneuploid sake yeast. Pyruvic Acid cytochrome-c peroxidase Saccharomyces cerevisiae S288C