Title : Efficient cleavage by alpha-thrombin of a recombinant fused protein which contains insulin-like growth factor I.

Pub. Date : 1987 Dec

PMID : 3334100






2 Functional Relationships(s)
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Protein Name
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1 A fusion protein connected through a tetradecapeptide (Asp-Asp-Pro-Pro-Thr-Val-Glu-Leu-Gln-Gly-Leu-Val-Pro-Arg) was efficiently and correctly cleaved by alpha-thrombin, and the purified IGF-I possessed somatomedin-like activity, as determined by the enhancement of sulfation of glycosaminoglycans in cultured costal chondrocytes from rabbits. Threonine insulin-like growth factor I Oryctolagus cuniculus
2 A fusion protein connected through a tetradecapeptide (Asp-Asp-Pro-Pro-Thr-Val-Glu-Leu-Gln-Gly-Leu-Val-Pro-Arg) was efficiently and correctly cleaved by alpha-thrombin, and the purified IGF-I possessed somatomedin-like activity, as determined by the enhancement of sulfation of glycosaminoglycans in cultured costal chondrocytes from rabbits. Glycosaminoglycans insulin-like growth factor I Oryctolagus cuniculus