Title : Interaction of BDE-47 with nuclear receptors (NRs) based on the cytotoxicity: In vitro investigation and molecular interaction.

Pub. Date : 2021 Jan 15

PMID : 33049448






2 Functional Relationships(s)
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1 Taking the number of hydrogen bonds and ZDock scores into account, the rank of docking ability between RXRalpha and the NRs was PXR > TRbeta > PPARgamma. Hydrogen retinoid X receptor alpha Homo sapiens
2 The results of this study demonstrated that BDE-47 interfered the cross-talk among NRs, especially the promiscuous RXRalpha, which might be critical for the harmonized re-adjustment of cytotoxicity and biological regulation. 2,2',4,4'-tetrabromodiphenyl ether retinoid X receptor alpha Homo sapiens