Title : Bioconcentration of 2,4,6-tribromophenol (TBP) and thyroid endocrine disruption in zebrafish larvae.

Pub. Date : 2020 Dec 15

PMID : 32871520






3 Functional Relationships(s)
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1 Gene transcription levels in the hypothalamic-pituitary-thyroid (HPT) axis were also examined in larvae; these results revealed that the transcription of corticotrophin-releasing hormone (crh), thyrotropin-releasing hormone (trh), and thyroid-stimulating hormone (tshbeta) were all significantly downregulated by exposure to TBP. 2,4,6-tribromophenol corticoliberin Danio rerio
2 Further, the gene transcription and protein expression of binding and transport protein transthyretin (TTR) were significantly increased after TBP exposure. 2,4,6-tribromophenol transthyretin (prealbumin, amyloidosis type I) Danio rerio
3 Further, the gene transcription and protein expression of binding and transport protein transthyretin (TTR) were significantly increased after TBP exposure. 2,4,6-tribromophenol transthyretin (prealbumin, amyloidosis type I) Danio rerio