Title : Evidence for Noncytosine Epigenetic DNA Modifications in Multicellular Eukaryotes: An Overview.

Pub. Date : 2021

PMID : 32822019






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1 Here we review experimental evidence for the presence of noncytosine epigenetic modifications in metazoans and plants focusing on two "unusual" DNA bases, 5-hydroxymethyluracil (5hmU) and N6-methyladenine (6mA), and suggest potential explanations for inconsistencies in the currently available data on abundance and potential biological roles of these DNA modifications in mammals. 5-hydroxymethyluracil HMU Homo sapiens