Title : Pseudohyphal differentiation in Komagataella phaffii: investigating the FLO gene family.

Pub. Date : 2020 Aug 1

PMID : 32766781






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Transcriptional analysis identified that FLO11, FLO400 and FLO5-1 are involved in the phenotype, all being controlled by the transcriptional regulator Flo8. flo8 Flo11p Saccharomyces cerevisiae S288C
2 In contrast, deletion of FLO400 or FLO5-1 prevents pseudohyphae formation, and hampers FLO11 expression. flo400 Flo11p Saccharomyces cerevisiae S288C
3 Our findings indicate that K. phaffii Flo400 and/or Flo5-1 act as upstream signals that lead to the induction of FLO11 upon glucose limitation in chemostats at slow growth and chromatin modulation is involved in the regulation of their expression. Glucose Flo11p Saccharomyces cerevisiae S288C