Pub. Date : 2020 Aug
PMID : 32434809
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The Role of Lysosome-Associated Membrane Protein 2 in Prostate Cancer Chemopreventive Mechanisms of Sulforaphane. | sulforaphane | lysosomal associated membrane protein 2 | Homo sapiens |
| 2 | Western blotting revealed dose-dependent induction of LAMP2 protein after treatment with SFN as well as its naturally-occurring analogs in PC-3 and 22Rv1 human prostate cancer cell lines that was confirmed by microscopy (SFN). | sulforaphane | lysosomal associated membrane protein 2 | Homo sapiens |
| 3 | Apoptosis induction by SFN treatment was also increased significantly by knockdown of the LAMP2 protein in PC-3 and 22Rv1 cells. | sulforaphane | lysosomal associated membrane protein 2 | Homo sapiens |
| 4 | In conclusion, the present study reveals that induction of LAMP2 by SFN inhibits its ability to induce apoptotic cell death at least in human prostate cancer cells. | sulforaphane | lysosomal associated membrane protein 2 | Homo sapiens |