Title : O-glycan initiation directs distinct biological pathways and controls epithelial differentiation.

Pub. Date : 2020 Jun 4

PMID : 32329196






1 Functional Relationships(s)
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1 We demonstrate that loss of individual GalNAc-T isoforms causes distinct epithelial phenotypes through their effect on specific biological pathways; GalNAc-T1 targets are associated with components of the endomembrane system, GalNAc-T2 targets with cell-ECM adhesion, and GalNAc-T3 targets with epithelial differentiation. N-acetylgalactosaminuronic acid polypeptide N-acetylgalactosaminyltransferase 2 Homo sapiens