Pub. Date : 2020 Jun
PMID : 32293069
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Basal reactive oxygen species (ROS), NOX activity, and blood pressure (BP) were also higher in Snx1-/- mice, which were normalized by apocynin, a drug that prevents NOX assembly. | acetovanillone | sorting nexin 1 | Mus musculus |
| 2 | siRNA-mediated depletion of SNX1 in RPT cells from NT subjects led to a blunting of D5 R agonist-induced increase in cAMP production and decrease in Na+ transport, effects that were normalized by over-expression of SNX1. | Cyclic AMP | sorting nexin 1 | Mus musculus |
| 3 | Among HT African-Americans, three of the 12 single nucleotide polymorphisms interrogated for the SNX1 gene were associated with a decrease in systolic BP in response to hydrochlorothiazide (HCTZ). | Hydrochlorothiazide | sorting nexin 1 | Mus musculus |
| 4 | Among HT African-Americans, three of the 12 single nucleotide polymorphisms interrogated for the SNX1 gene were associated with a decrease in systolic BP in response to hydrochlorothiazide (HCTZ). | Hydrochlorothiazide | sorting nexin 1 | Mus musculus |