Title : Aminoacyl-tRNA synthetase inhibition activates a pathway that branches from the canonical amino acid response in mammalian cells.

Pub. Date : 2020 Apr 21

PMID : 32253314






1 Functional Relationships(s)
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Protein Name
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1 Like HF, the threonyl-tRNA synthetase inhibitor borrelidin suppresses the induction of tissue remodeling and inflammatory mediators in cytokine-stimulated fibroblast-like synoviocytes without GCN2, but both aminoacyl-tRNA synthetase (aaRS) inhibitors are sensitive to the removal of GCN1. borrelidin threonyl-tRNA synthetase 1 Homo sapiens